It's possible, but we don't recommend it.
Although one can easily enjoy a full day or more at both parks, to visitors with limited time we recommend a minimum of three to four hours to see some of the Zoo and a minimum of four to six hours to experience a portion of the Safari Park.
The Zoo and Safari Park are approximately 35 miles apart from each other. The drive time between the two parks is about 45 minutes to one hour, depending on traffic and other factors. The Zoo is located in Balboa Park, just north of downtown San Diego, at 2920 Zoo Drive, San Diego, CA 92108. The Safari Park is located at 15500 San Pasqual Valley Road, Escondido, California 92027, a remote area of Escondido. Following the directions on our website, a well-traveled, two-lane country road comprises approximately five of the last six miles leading to the Safari Park. Occasional traffic delays may occur along this road on peak attendance days (holidays; weekends during spring break, summer and December).
Well known for its 100 acres of lush, naturalistic habitats and unique animal encounters, the San Diego Zoo is home to more than 3,700 rare and endangered animals (including pandas, koalas, tigers, polar bears, and more) representing approximately 660 species and subspecies and a prominent botanical collection with more than 700,000 plants.
The 1,800–acre Safari Park is home to more than 3,000 animals representing over 300 species, many living in open field habitats. In addition, the Park has a renowned botanical collection with more than 1.7 million plants.
For these reasons and to get the most from an unhurried visit, we strongly recommend visiting our parks on separate days.